Fabrication of Highly Porous Interconnected Three-dimensional Scaffolds with Micro-channels

来源 :Chinese Journal of Polymer Science | 被引量 : 0次 | 上传用户:cubqfire
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A novel highly porous 3-D poly(ε-caprolactone)(PCL) scaffold with micro-channels was fabricated by injection molding and diluent acetic acids leaching technologies. In this study, the chitosan fiber was employed to form the microchannel in PCL matrix. The morphology, porosity and mechanical properties of the scaffolds were studied and calculated. It was found that the larger the content of chitosan fiber is, the higher the porosity would be, due to the volumetric expansion of chitosan fiber in PCL matrix during it being leached. In addition, the less the content of chitosan fiber is, the higher the compressive modulus would be. A novel highly porous 3-D poly (ε-caprolactone) (PCL) scaffold with micro-channels was fabricated by injection molding and diluent acetic acid leaching technologies. In this study, the chitosan fiber was employed to form the microchannel in PCL matrix. The was the found, the greater the content of chitosan fiber is, the higher the porosity would be, due to the volumetric expansion of chitosan fiber in PCL matrix during it being leached . In addition, the less the content of chitosan fiber is, the higher the compressive modulus would be.
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