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目的探讨阔韧带巨大淋巴管平滑肌瘤病临床病理学特点及其诊断与鉴别诊断。方法对活检组织进行组织学观察及免疫组化检测,并复习文献进行研究。结果右侧阔韧带肿物为大小不等的网状腔隙状组织,管壁为增生的短梭形平滑肌细胞。免疫组化:ER和PR(■),SMA、actin和desmin(■),melan A、CD56和CD99(+)。结论淋巴管平滑肌瘤病是一种罕见的肿瘤性疾病。根据临床表现、组织学特征及免疫组化有助于该瘤的诊断与鉴别诊断。
Objective To investigate the clinicopathological features of broad lymphatic leiomyomata and its diagnosis and differential diagnosis in broad ligament. Methods Histological observation and immunohistochemistry were performed on the biopsies and the literature was reviewed. The results of the right broad ligament tumor of varying sizes of network lamellar tissue, wall proliferation of short spindle smooth muscle cells. Immunohistochemistry: ER and PR (■), SMA, actin and desmin (■), melan A, CD56 and CD99 (+). Conclusion Lymphangioleiomyomatosis is a rare neoplastic disease. According to clinical manifestations, histological features and immunohistochemistry contribute to the diagnosis and differential diagnosis of the tumor.