目的探讨沐舒坦静脉推注联合雾化吸入辅助治疗慢性阻塞性肺疾病(COPD)的临床疗效。方法60例COPD患者随机分为治疗组和对照组,治疗组将沐舒坦针剂静脉推注联合超声雾化吸入治疗,而对照组仅予单纯沐舒坦针剂静脉推注治疗。结果治疗组的显效率明显高于对照组,差异有统计学意义(P<0.05),而两组总有效率分别为93.3%和90.0%,差异无统计学意义(P>0.05)。结论沐舒坦静脉推注联合雾化吸入治疗与单纯沐舒坦静脉推注治疗对慢性阻塞性肺疾病均取得良好的疗效,但沐舒坦静脉推注联合雾化吸入治疗对咳嗽、咳痰症状改善尤为明显,提示沐舒坦雾化吸入治疗对痰液黏稠、排痰困难有着独到的临床效果。 Objective To investigate the clinical efficacy of mucosolvan intravenous injection combined with atomization inhalation in the treatment of chronic obstructive pulmonary disease (COPD). Methods Sixty COPD patients were randomly divided into treatment group and control group. In the treatment group, Mucosolvan was injected intravenously in combination with ultrasonic atomization inhalation, while in the control group, only Mucosolvan was injected intravenously. Results The effective rate of the treatment group was significantly higher than that of the control group, the difference was statistically significant (P <0.05), while the total effective rate was 93.3% and 90.0% respectively, with no significant difference (P> 0.05). Conclusion Mucosolvan intravenous injection combined with atomized inhalation therapy and simple mucosolvan intravenous injection therapy have good effect on chronic obstructive pulmonary disease, but the combination of mucosolvan intravenous injection and nebulized inhalation has a significant effect on the improvement of cough and sputum symptoms Obviously, suggesting that mucosolvan inhalation on sputum mucus viscosity, difficult to expectoration has a unique clinical effect.