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随着对肿瘤与免疫关系的认识逐渐深入,免疫学在肿瘤方面的应用日益增多,许多学者试图寻找简便灵敏的免疫检测方法。1972年Halliday等发现,白细胞有粘附于玻璃表面的特性,当加入相应的肿瘤抗原时,粘附则受到抑制,将此现象称为“白细胞粘附抑制现象”,并用此原理进行白细胞粘附抑制(Leukocyte adherence inhibition,LAI)试验来检测肿瘤特异性免疫反应。以后,国内外许多学者应用此法,证实LAI可准确的反应肿
With the gradual deepening of the understanding of the relationship between tumor and immune system, the application of immunology in cancer has been increasing day by day. Many scholars try to find a simple and sensitive immunoassay. In 1972, Halliday et al. Found that leukocytes have the property of adhering to the surface of the glass. When the corresponding tumor antigens are added, the adhesion is inhibited. This phenomenon is called “leukocyte adhesion inhibition phenomenon” and is used for leukocyte adhesion Leukocyte adherence inhibition (LAI) assay to detect tumor-specific immune responses. Later, many scholars at home and abroad use this method to confirm that LAI can accurately respond to swollen