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表皮生长因子(EGF)和转铁蛋白(TF)是两种可溶性分子。EGF是一种低分子量的多肽,存在于大多数体液中,能促进人体内上皮和非上皮组织及培养基中的多种类型细胞的增生与分化。EGF还可见于胎儿的组织和羊水中。转化生长因子-α(TGF-α)也是一种肽类,与EGF结构相似,TGF-α首先在转化的细胞中鉴定出,随后在胚胎组织中以及在几种正常成人的细胞(包括角朊细胞)中检出。TF是一种血清糖蛋白,它能将铁传递给细胞。现已证实,TF在不含血清的培养基中对正常细胞或肿
Epidermal growth factor (EGF) and transferrin (TF) are two soluble molecules. EGF is a low-molecular-weight polypeptide found in most body fluids that promotes proliferation and differentiation of many types of cells in epithelial and non-epithelial tissues and in the human body. EGF is also found in fetal tissues and amniotic fluid. Transforming growth factor-alpha (TGF-alpha) is also a type of peptide that, similar to the EGF structure, is first identified in transformed cells and subsequently in embryonic tissue and in several normal adult cells, including keratin Cells). TF is a serum glycoprotein that delivers iron to cells. Has been confirmed, TF in serum-free medium on normal cells or swollen