长柄千金藤Stephania longipes H.S,Lo,又名藤子绿色、猴子板凳,分布于云南临沧、保山一带。我们自其提取颅痛定(左旋四氧巴马汀)后的剩余生物碱中分离出一种生物碱,经理化试验及四谱测定,确定为光千金藤定碱(stepholidine)。光千金藤定碱具有镇痛、镇静等约理作用,小鼠按50mg/kg灌胃,热板法T值测定:20分钟(P<0.01),40分钟(P<0.001),持续到420分钟(P<0.05)。镇痛效果约为吗啡85%。小鼠灌胃LD_(50)为943mg/kg,其热体法ED_(50)为173mg/kg。在药理试验过程中,尚未 Stephania longipes H.S, Lo, also known as Fujiko green, monkey bench, is located in the Linyi and Baoshan areas of Yunnan. We isolated an alkaloid from the remaining alkaloids after its extraction from tetrandrine (L-tetrahydropalmatine). The results were determined by a managerial test and four-spectrum assay, which was identified as stepholidine. Calcitendine has anecdotal effects such as analgesia and sedation. The mice were intragastrically administered at 50 mg/kg, and the hot plate method T values ​​were measured at 20 minutes (P<0.01) and 40 minutes (P<0.001), continuing to 420. Minutes (P<0.05). The analgesic effect is about 85% of morphine. The LD_(50) was 943 mg/kg in mice, and the ED_(50) was 173 mg/kg. During the pharmacological test, not yet