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目的 评价多中心型Castleman病 (CD)的CT表现。方法 回顾性分析 1例经淋巴结活检证实的多中心型CD患者的胸、腹部CT表现 ,并作文献复习。结果 患者具有全身症状 ,多克隆性高丙球蛋白血症 ,全身浅深淋巴结广泛肿大并增强扫描轻度强化 (约 2 0HU) ,肺实质出现特异性浸润 ,包括小叶中心性分布的弥漫小结节、磨玻璃灶、薄壁气囊、支气管血管束和小叶间隔增厚 ,与文献高度一致。结论 多中心型CD具有明显的临床全身症状、全身广泛的淋巴结肿大并轻中度强化 ,侵犯肺实质时病变有一定特点 ,典型表现可提示本病。
Objective To evaluate the CT findings of multicenter Castleman disease (CD). Methods A retrospective study was performed on the CT findings of chest and abdomen in a multicentric CD patient confirmed by lymph node biopsy. Results Patients with systemic symptoms, polyclonal hypergammaglobulinemia, generalized deep superficial lymph nodes with extensive enlargement and enhanced scan mild enhancement (about 20 HU), with specific infiltration of lung parenchyma, including diffuse small nodules with centrilobular distribution , Ground glass stove, thin-walled balloon, bronchovascular bundle and interlobular septal thickening, highly consistent with the literature. Conclusions Multi-center CD has obvious clinical symptoms, extensive lymphadenopathy and mild to moderate enhancement. The lesions have some characteristics when infiltrating the parenchyma of the lung, and the typical manifestation may indicate the disease.