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目的评价无肝素冠状动脉造影术的可行性及安全性。方法总结分析1400例经股动脉行无肝素冠状动脉造影术的患者的临床资料并与354例普通肝素冠状动脉造影术患者进行对照。结果99.3%的病例行选择性冠脉造影成功,手术时间(从穿刺动脉到造影结束)8min ̄1h,平均(17.9±11.3)min。冠心病阳性率为72.2%,多支血管病变占49.8%。皮下血肿的发生率为1.8%,假性动脉瘤和动静脉瘘发生率为0.07%,腹膜后血肿、急性心肌梗死、脑卒中及其他体循环栓塞事件发生率为0。结论无肝素冠状动脉造影术不仅安全且具有外周血管并发症少、痛苦小、住院时间短等优点。
Objective To evaluate the feasibility and safety of heparin-free coronary angiography. Methods The clinical data of 1400 patients undergoing heparin-free coronary angiography through the femoral artery were analyzed and compared with 354 patients undergoing unfractionated heparin coronary angiography. Results 99.3% of patients underwent selective coronary angiography. The operation time (from perforating artery to the end of radiography) was 8 min to 1 h, with an average of (17.9 ± 11.3) min. Coronary heart disease positive rate was 72.2%, multivessel disease accounted for 49.8%. The incidence of subcutaneous hematoma was 1.8%. The incidence of pseudoaneurysm and arteriovenous fistula was 0.07%. The incidence of retroperitoneal hematoma, acute myocardial infarction, stroke and other systemic embolism events was 0%. Conclusion Non-heparin coronary angiography is not only safe but also has fewer peripheral vascular complications, less pain and shorter hospital stay.