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[目的]了解无症状HIV感染者与正常人的CD3、CD、CD45淋巴细胞绝对数及CD3/CD45、CD4/CD45情况。[方法]采用BD FACSCalibur流式细胞仪分别检测117例健康成人血液标本和87名无症状HIV感染者中的CD3、CD4、CD45淋巴细胞绝对数及CD3/CD45、CD4/CD45的比值,进行统计学分析。[结果]无症状HIV感染者男性与女性相比除CD3/CD45有统计学差异外(t=3.23,P﹤0.05),其余几项指标均无统计学差异。但与正常人相比较比较CD3、CD4、CD3/CD45、CD4/CD45、CD45均存在统计学差异。[结论]当HIV感染者CD4细胞减少的还不是十分明显(未小于200个/μl),但发现感染者CD4/CD45的比值开始持续明显变小时,应开始考虑对感染者进行治疗。
[Objective] To understand the absolute numbers of CD3, CD, CD45 lymphocytes and CD3 / CD45, CD4 / CD45 in asymptomatic HIV-infected and normal subjects. [Methods] The absolute numbers of CD3, CD4, CD45 lymphocytes and the ratio of CD3 / CD45, CD4 / CD45 in 117 healthy adult blood samples and 87 asymptomatic HIV-infected persons were detected by BD FACSCalibur flow cytometry Analysis. [Results] There was no significant difference between the male and female in asymptomatic HIV infection except CD3 / CD45 (t = 3.23, P <0.05). However, compared with normal people, there were significant differences in CD3, CD4, CD3 / CD45, CD4 / CD45 and CD45. [Conclusion] When the CD4 count in HIV-infected persons is still not significantly reduced (no less than 200 / μl), it should be considered to treat the infected patients when the ratio of CD4 / CD45 in infected persons begins to decrease significantly.