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目的探讨高敏C反应蛋白(hs-CRP)和B型钠尿肽(BNP)联合检测对心力衰竭(HF)诊断和预后判断的价值。方法检测100例明确诊断为HF的不同原因、不同心功能分级的患者入院时及出院时血清hs-CRP和血浆BNP水平,并与50名健康对照组比较,随访观察患者心血管事件的再发生情况。结果血清hs-CRP和血浆BNP在HF患者不同心功能分级组和对照组之间差异均有统计学意义,且与心功能成正比。结论血液中hs-CRP和BNP的含量可以作为心力衰竭病情进展情况的一个有效地指标,为心力衰竭的治疗提供一定的参考。
Objective To investigate the diagnostic value of high-sensitivity C-reactive protein (hs-CRP) and B-type natriuretic peptide (BNP) in the diagnosis and prognosis of heart failure. Methods The serum hs-CRP and plasma BNP levels of 100 patients with definite diagnosis of HF, with different cardiac function scores at admission and at discharge were detected and compared with 50 healthy controls. Follow-up was performed to observe the recurrence of cardiovascular events Happening. Results The serum levels of hs-CRP and plasma BNP in HF patients with different cardiac function grading group and control group were statistically significant, and with cardiac function is proportional to. Conclusion The blood levels of hs-CRP and BNP can be used as an effective indicator of the progression of heart failure and provide some reference for the treatment of heart failure.