论文部分内容阅读
中药防病治病的物质基础是其所含有效成分,且大部分成分结构未知。以中药所含化学成分全面分析为目的,建立并发展多组分物质分析的概念,由此提出了适于中药中目标及非目标化学成分的分析方法。以中药非目标化合物分析为背景,以LC-MS技术手段为依托,从仪器技术和方法设计两方面阐述当前的非目标化合物研究情况,着重探讨了该领域不同试验方法设计的特色与局限性。
The material basis of prevention and treatment of traditional Chinese medicine is that it contains the active ingredient, and most of the ingredients are unknown in structure. With the purpose of comprehensive analysis of the chemical components contained in traditional Chinese medicine, the concept of multi-component material analysis was established and developed, and the analytical methods suitable for target and non-target chemical components in traditional Chinese medicine were proposed. Based on the analysis of non-target compounds in traditional Chinese medicine (TCM), and based on LC-MS techniques, the current research on non-target compounds was elaborated from the aspects of instrumental techniques and method design. The characteristics and limitations of different experimental methods in this field were also discussed.