在KOH溶液中,芳甲酰肼(2)与CS2生成钾盐3;然后3在水合肼作用下经过环化、取代、肼解得3-巯基-4-氨基-5-苯基-4H-1,2,4-三唑-乙酸酰肼(6),6再与CS2回流成环生成化合物5-(4-氨基-5-苯基-4H-1,2,4-三唑-3-硫烷基)-1,3,4-噁二唑-2-硫醇(7),最后7与取代苄基氯反应得目标化合物A1～A6,与芳基甲醛反应得终产物B1～B15.目标化合物的结构均经1H NMR,13C NMR,IR,MS或HRMS确证结构. In KOH solution, aroyl hydrazide (2) forms CS3 with CS2; then 3 is cyclized and substituted with hydrazine hydrate to give 3-mercapto-4-amino-5-phenyl-4H- 1,2,4-triazole-acetic acid hydrazide (6), which is then recycled to CS2 to form the compound 5- (4-amino-5-phenyl-4H-1,2,4-triazol- Sulfanyl) -1,3,4-oxadiazole-2-thiol (7). Finally, the target compounds A1 ~ A6 are reacted with substituted benzyl chloride to react with aryl formaldehydes to obtain the final products B1 ~ B15. The structures of the target compounds were confirmed by 1H NMR, 13C NMR, IR, MS or HRMS.