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目的利用每天平均每小时代谢当量(MET)水平来评价体力活动与缺血性心血管疾病(ICVD)的关系。方法1998年秋季对不同地区35～59岁人群进行心血管危险因素抽样调查,并对调查时无冠心病、脑卒中及恶性肿瘤病史的个体进行随访至2005年上半年。结果共有11849名研究对象资料完整,平均随访5．9年,共发生84例ICVD事件。将MET值作为连续变量带入Cox回归模型研究其与心血管发病风险的关系,初步调整人口学因素后总人群、男性、女性、城市及农村人群发病风险均与MET值负相关,其中城市人群有统计学意义HR=0．22(95% CI：0．05～0 95)。进一步调整其他因素后相关性减弱,城市人群显著性消失。结论城市人群平均每小时MET水平与ICVD呈负相关,其对心血管病的保护可能主要通过传统危险因素起作用。
Objective To evaluate the relationship between physical activity and ischemic cardiovascular disease (ICVD) by using mean daily metabolic equivalent (MET) levels per day. Methods In the autumn of 1998, samples of cardiovascular risk factors from 35 to 59 years old in different areas were surveyed. Individuals with no history of coronary heart disease, stroke and malignancy were followed up till the first half of 2005. Results A total of 11,849 study subjects were complete with an average follow-up of 5.9 years. A total of 84 ICVD events occurred. MET was taken as a continuous variable into the Cox regression model to study its relationship with the risk of cardiovascular disease. After preliminary adjustment of demographic factors, the risk of total population, male, female, urban and rural population were negatively correlated with MET, of which urban population There was a statistically significant HR = 0.22 (95% CI: 0.05-095). After adjusting for other factors, the correlation decreased and the urban population disappeared significantly. Conclusions The average hourly MET level in urban population is negatively correlated with ICVD, and its protection against cardiovascular disease may play its role mainly through traditional risk factors.