迄今已有不少体内研究,提示于放射期间组织细胞内cAMP浓度增加县有辐射保护作用(radioprotec-tire effect)。因此,不少研究者于放射前给予注射二丁基cAMP,这样可以增加诸如毛囊细胞,小肠干细胞的存活,另一方面,对于纤维肉瘤的微小转移灶(micrometastases)以及可移植性乳腺腺癌则无这种辐射保护作用。本文旨在使用cAMP磷酸二脂酶的抑 Up to now, there have been many in vivo studies, suggesting that the intracellular cAMP concentration in tissue cells increases during radiation and the radioprotec-tire effect is observed in the county. Therefore, many investigators injected dibutyl cAMP before radiation, which could increase the survival of hair follicle cells, intestinal stem cells, and on the other hand, micrometastases of fibrosarcoma and transplantable breast adenocarcinoma. No such radiation protection. This article aims to use cAMP phosphodiesterase inhibitors