论文部分内容阅读
目的探讨适宜水碘含量的上限阈值。方法在河北省停供碘盐的5个市髙碘地区,选择水碘含量在20-310μg/L之间的12个村,采集尿样、水样和居民户食用盐,调查居民饮用水的碘含量和8-10岁儿童的尿碘含量之间的关系。结果 12个调查村水碘中位数在29.0-307.8μg/L之间,8-10岁儿童尿碘中位数在240.0-458.9μg/L之间。采用Spearman等级相关分析(R=0.951,P=0.000),儿童的尿碘中位数与其所在村的水碘中位数呈正相关。直线回归分析发现,儿童尿碘含量的变化中有88.9%与水碘含量的变化有关。线性回归方程为y=0.676x+225.6,当尿碘中位数为300μg/L时,水碘中位数为110μg/L。结论高碘地区水碘含量是影响儿童尿碘含量的主要因素,适宜水碘含量上限阈值为110μg/L。
Objective To investigate the upper limit of suitable iodine content in water. Methods In the five municipal 髙 iodine areas where iodized salt was stopped in Hebei Province, 12 villages with water iodine levels of 20-310 μg / L were selected to collect urine samples, water samples and household salt for residents’ drinking water Relationship between iodine content and urinary iodine content in children aged 8-10 years. Results The median of iodine in 12 investigated villages was 29.0-307.8μg / L, and the median urinary iodine of children aged 8-10 was between 240.0-458.9μg / L. Using Spearman rank correlation analysis (R = 0.951, P = 0.000), the median urinary iodine in children was positively correlated with the median of water iodine in their village. Linear regression analysis found that 88.9% of children with changes in urinary iodine content and changes in water iodine content. The linear regression equation was y = 0.676x + 225.6. When the urinary iodine median was 300μg / L, the median of water iodine was 110μg / L. Conclusion The water iodine content in high iodine area is the main factor affecting urinary iodine content in children. The upper limit of appropriate iodine content is 110μg / L.