论文部分内容阅读
目的探究腹腔镜直肠癌根治术根治肿瘤的临床效果与安全性。方法 30例直肠癌患者,随机分为常规组和实验组,每组15例。常规组患者采取开腹根治术,实验组患者实施腹腔镜直肠癌根治术。统计对比两组的术后炎症因子水平以及治疗1年后的远处转移和复发情况。结果实验组患者的白细胞介素-6、肿瘤坏死因子-α以及C反应蛋白水平均优于常规组,差异具有统计学意义(t=2.41、4.93、2.12,P<0.05)。治疗1年后,实验组患者的远处转移率为6.7%、复发率为6.7%,均显著低于常规组的53.3%、66.7%,差异具有统计学意义(P<0.05)。结论直肠癌经腹腔镜直肠癌根治术治疗的安全性较高,可使患者炎症反应得到改善,远处转移率与复发率均较低,值得推广。
Objective To investigate the clinical effect and safety of laparoscopic radical resection of rectal cancer. Methods Thirty patients with rectal cancer were randomly divided into routine group and experimental group, 15 cases in each group. The patients in the conventional group were treated with laparotomy and the patients in the experimental group underwent laparoscopic radical resection of rectal cancer. Statistics were compared between the two groups of postoperative inflammatory cytokines levels and distant metastasis and recurrence after 1 year of treatment. Results The levels of interleukin-6, tumor necrosis factor-α and C-reactive protein in the experimental group were significantly higher than those in the conventional group (t = 2.41, 4.93, 2.12, P <0.05). One year after treatment, the distant metastasis rate and the recurrence rate in the experimental group were 6.7% and 6.7%, respectively, which were significantly lower than those in the conventional group (53.3% and 66.7%, P <0.05). Conclusions The safety of laparoscopic radical resection of rectal cancer in rectal cancer is high, which can improve the inflammatory response, distant metastasis rate and recurrence rate in lower rectal cancer, which is worthy of popularization.