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目的:观察中西医结合治疗老年肺炎临床疗效。方法:将老年肺炎患者68例分为2组各34例,对照组给予常规治疗,观察组在对照组的治疗基础上根据不同的中医辨证进行治疗。比较2组血常规、免疫功能、T细胞亚群的变化以及临床转归。结果:治疗7天后观察组血常规显著恢复,白细胞计数、血小板计数、中性粒细胞以及淋巴细胞均值与对照组比较,差异有统计学意义(P<0.05)。治疗7天后观察组CD3~+、CD4~+水平低于对照组,CD8~+高于对照组,差异有统计学意义(P<0.05)。治疗7天后观察组IgG、IgA以及IgM水平均升高但较对照组低(P<0.05)。治疗7天后观察组好转出院率高于对照组,无效率及死亡率低于对照组(P<0.05)。结论:中西医结合治疗老年肺炎可改善高凝状态,调节肺炎患者的各项免疫功能,降低炎症反应。
Objective: To observe the clinical efficacy of traditional Chinese and western medicine in the treatment of senile pneumonia. Methods: 68 elderly patients with pneumonia were divided into two groups of 34 cases, the control group given conventional treatment, the observation group in the control group based on the treatment of different TCM syndrome differentiation treatment. The blood routine, immune function, changes of T cell subsets and clinical outcome were compared between the two groups. Results: After 7 days of treatment, the blood routine of the observation group was significantly recovered. The white blood cell count, platelet count, neutrophil and lymphocyte mean were significantly different from those of the control group (P <0.05). After 7 days of treatment, the level of CD3 ~ + and CD4 ~ + in the observation group was lower than that in the control group, and the level of CD8 + was higher in the observation group than in the control group (P <0.05). After 7 days of treatment, the levels of IgG, IgA and IgM in the observation group were all higher than those in the control group (P <0.05). After 7 days of treatment, the improvement rate of discharge in the observation group was higher than that in the control group, and the inefficiency and mortality rate were lower than those in the control group (P <0.05). Conclusion: The combination of traditional Chinese and Western medicine treatment of elderly pneumonia can improve the hypercoagulable state, regulate the immune function of patients with pneumonia and reduce the inflammatory reaction.