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目的分析北京市昌平区成年人甘油三酯/高密度脂蛋白胆固醇(TG/HDL-C)水平与糖尿病和糖尿病前期患病的关系。方法研究对象为参加2013年北京市昌平区卫生与人群健康状况调查的18~79岁昌平区常住居民。研究对象个人信息通过问卷调查获得。根据TG/HDL-C在人群中分布情况,对男性及女性TG/HDL-C分别按照四分位数法分组。研究结局包括糖尿病、糖尿病前期以及糖尿病和糖尿病前期。结果调查对象3895人,其中男性1745人,女性2150人。调查结果显示,糖尿病患者、糖尿病前期人群、糖尿病和糖尿病前期患者分别为413、1016和1429人。经多因素logistic模型分析,在男性人群中,与<0.66组相比,1.08~1.74组和≥1.75组糖尿病患病风险OR值(95%CI)分别为2.23(1.35~3.68)和2.36(1.43~3.91);糖尿病和糖尿病前期患病风险OR值(95%CI)分别为1.38(1.01~1.87)和1.80(1.32~2.45);≥1.75组糖尿病前期患病风险OR值(95%CI)为1.58(1.13~2.21)。在女性人群中,与<0.57组相比,0.83~1.30组和≥1.31组糖尿病患病风险OR值(95%CI)分别为2.65(1.56~4.49)和3.72(2.23~6.22);糖尿病前期患病风险OR值(95%CI)分别为1.60(1.16~2.20)和2.20(1.59~3.04);糖尿病和糖尿病前期病患病风险OR值(95%CI)分别为1.78(1.32~2.39)和2.55(1.88~3.44)。结论随着TG/HDL-C水平的增加,糖尿病患病风险以及糖尿病前期患病风险均逐渐升高。
Objective To analyze the relationship between the levels of triglyceride / high density lipoprotein cholesterol (TG / HDL-C) and the prevalence of diabetes and pre-diabetes in Changping District of Beijing. Methods The study participants were Chang-Chang District residents aged 18-79 who participated in the survey of health status and population health in Changping District in Beijing in 2013. Among them, The personal information of the respondents was obtained through questionnaire survey. According to the distribution of TG / HDL-C in the population, the TG / HDL-C of men and women were grouped according to the quartile method. Findings include diabetes mellitus, pre-diabetes, and pre-diabetes and diabetes. Results The survey of 3895 people, of which 1745 were males and 2150 females. The survey showed that patients with diabetes, pre-diabetes, diabetes and pre-diabetes patients were 413,1016 and 1429 people. In multivariate logistic model analysis, in the male population, the odds ratios (95% CI) of prevalence of diabetes in 1.08-1.74 group and ≥1.75 group were 2.23 (1.35-3.68) and 2.36 (1.43 ~ 3.91). The odds ratio (95% CI) of prevalence of diabetes and pre-diabetes were 1.38 (1.01-1.87) and 1.80 (1.32-2.45) respectively. The odds ratio (95% CI) 1.58 (1.13 ~ 2.21). In the female population, the odds ratio (95% CI) of prevalence of diabetes in the 0.83-1.30 group and ≥1.31 group was 2.65 (1.56-4.49) and 3.72 (2.23-6.22), respectively, compared with <0.57 group; OR of 95% CI was 1.60 (1.16-2.20) and 2.20 (1.59-3.04) respectively. The odds ratio (95% CI) of prevalence of diabetes and pre-diabetes were 1.78 (1.32-2.39) and 2.55 (1.88 ~ 3.44). Conclusion With the increase of TG / HDL-C, the risk of diabetes and the risk of pre-diabetes are gradually increased.