临床资料患者,男,67岁。主因双手背和面颈部红斑、瘙痒反复发作10余年,渐进性加重3个月,泛发全身10余d,于2013年2月入院。10年前患者双手背出现红斑、瘙痒,诊断为接触性皮炎,皮损渐累及面部(以双颊部为主)、颈部,出现红斑、瘙痒,日晒后加重,期间在外院间断治疗(具体不详),病情时有反复;3个月前自觉面部红斑扩散,皮损加重,在外院诊断为慢性光化性皮炎,予沙利度胺、外用糖 Clinical data patients, male, 67 years old. Mainly due to both hands and face and neck erythema, itching repeated attacks for more than 10 years, progressive increase 3 months, generalized more than 10 d, admitted in February 2013. 10 years ago erythema and pruritus appeared on the back of the patient’s hands, contact dermatitis was diagnosed, contact of the face with cheek lesions (mainly cheeks), erythema and pruritus in the neck, and aggravating after sun exposure were observed. Specific unknown), the disease repeatedly; 3 months ago, conscious facial erythema spread, increased skin lesions, diagnosed in the outer courtyard of chronic actinic dermatitis, to thalidomide, topical sugar