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目的 测定不同地区钉螺对湖沼型地区日本血吸虫株的易感性 ,并进一步观察虫株的致病力变化。方法 用湖沼型地区日本血吸虫感染湖沼垸外型及垸内型、水网型、山丘型地区钉螺 ,之后以不同地区钉螺室内保种 (1代 )的尾蚴和原野外尾蚴感染家兔。结果 室内饲养的上述 4类地区钉螺的感染率分别为 49.5 8%、2 9.6 5 %、32 .0 1%、2 5 .2 5 % ;以 180 0条野外尾蚴和 4地区钉螺保种的尾蚴感染家兔后 ,各组平均虫负荷分别为 12 97、10 78、819、72 7、930条 ,家兔肝表面虫卵结节均数、每克肝虫卵均数、COPT反应率均为野外尾蚴组高于保种组 ,本地保种组高于异地各保种组。结论 湖沼垸外地区 (本地 )钉螺易感性高于异地 ,野外尾蚴的感染性和致病力高于保种组 ,保种组中本地组的感染率和致病力高于异地组
Objective To determine the susceptibility of Oncomelania snails to Schistosoma japonicum in lakes and marshes in different areas and to further observe the pathogenic changes of the strains. Methods Inoculation of lakes and marshes in the lakes and marshes region and the snail in the embankment, the water network and the hillsides were carried out. The rabbits were infected with cercariae and cercariae in the field after inoculation in different areas. Results The infection rates of snails in the above-mentioned four areas were 49.5 8%, 29.6%, 32.0% and 25.5% respectively. 180 coccidia and 4 ciliate After infected with rabbits, the average worm burden in each group was 1297, 1078, 819, 727, and 930, respectively. The average number of eggs on the liver surface of rabbits, the average number of eggs per gram of eggs and the response rate of COPT In the field cercariae group was higher than the conservation group, and the local species conservation group was higher than the other species conservation group in different places. Conclusion The susceptibility to snail in the area outside the lake was higher than that in other places. The infectivity and pathogenicity of cercariae in field were higher than that of the conservation group. The infection rate and pathogenicity of the local group in the conservation group were higher than those in the non-local group