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与可通过心肌肌钙蛋白(cardiac troponin,cTn)定量的心肌细胞坏死相反,功能性心肌细胞损伤(包括线粒体功能障碍)在急性心肌梗死(acute myocardial infarction,AMI)患者中的临床识别较不清晰。该研究旨在确定细胞色素C对AMI的诊断准确性及对院内死亡率的预测价值。方法:研究人员前瞻性评估了在两个队列(具有疑似AMI的患者的诊断队列,以及明确AMI患者的预后队列)中的医院检测的血清细胞
In contrast to cardiomyocyte necrosis, quantifiable by cardiac troponin (cTn), functional cardiomyocyte damage (including mitochondrial dysfunction) is less clearly identified in patients with acute myocardial infarction (AMI) . The aim of this study was to determine the diagnostic accuracy of cytochrome C for AMI and its predictive value for in-hospital mortality. METHODS: The researchers prospectively evaluated hospital-detected serum cells in two cohorts (diagnostic cohorts of patients with suspected AMI and prognostic cohorts of patients with definite AMI)