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在内分泌系统疾病的临床诊疗中.甲状腺癌是一种比较常见的恶性肿瘤.包括分化型甲状腺癌(滤泡状癌、乳头状癌)、未分化癌和髓样癌等病理组织类型.随着人们生活方式和饮食习惯的变化.甲状腺癌的发病率不断增高.其中主要的高危人群为中年妇女.目前.临床上主要采用CT、MRI、超声和放射性核素显像等影像学诊断来确诊.所谓分子影像学.就是Weissleder等人~([1])在1999年提出的.即通过无创性的影像学手段了解体内某些特定基因或蛋白质在生理或病理状态下的表达情况.对活体的生物过程进行定性和定量研究.为探索疾病的发生、发展和转归等在分子学领域提供了一条新思路。近年来分子影像学在甲状腺癌的诊断及靶向治疗的研究中取得了较大进展.本文就此进行综述如下.
In the clinical diagnosis and treatment of endocrine system diseases, thyroid cancer is a relatively common malignant tumor, including the types of pathological tissues such as differentiated thyroid carcinoma (follicular carcinoma, papillary carcinoma), undifferentiated carcinoma and medullary carcinoma. People’s lifestyle and diet changes.The incidence of thyroid cancer continues to increase.Among them, the main high-risk groups are middle-aged women.Currently, clinically mainly using CT, MRI, ultrasound and radionuclide imaging imaging diagnosis to confirm The so-called molecular imaging is Weissleder et al ~ ([1]) proposed in 1999. By noninvasive imaging methods to understand the body of certain genes or proteins in the physiological or pathological state of the expression of the living Of the biological process of qualitative and quantitative research for the discovery of disease, development and prognosis in the field of molecular science provides a new idea. In recent years, molecular imaging has made great progress in the research of diagnosis and targeted therapy of thyroid cancer.This article is summarized as follows.