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This study used electroacupuncture at Renzhong (DU26) and Baihui (DU20) in a rat model of cerebral ischemia/reperfusion injury. Neurological deficit scores, western blotting, and reverse transcription-PCR results demonstrated that electroacupuncture markedly reduced neurological deficits, decreased corpus striatum aquaporin-4 protein and mRNA expression, and relieved damage to the blood-brain barrier in a rat model of cerebral ischemia/reperfusion injury. These results suggest that electroacupuncture most likely protects the blood-brain barrier by regulating aquaporin-4 expression following cerebral ischemia/reperfusion injury.
This study used electroacupuncture at Renzhong (DU26) and Baihui (DU20) in a rat model of cerebral ischemia / reperfusion injury. Neurological deficit scores, western blotting, and reverse transcription-PCR results demonstrating that electroacupuncture markedly reduced neurological deficits, decreased corpus striatum aquaporin -4 protein and mRNA expression, and relieved damage to the blood-brain barrier in a rat model of cerebral ischemia / reperfusion injury. These results suggest that electroacupuncture most likely protects the blood- brain barrier by regulating aquaporin-4 expression following cerebral ischemia / reperfusion injury.