黄酮类化合物是广泛存在于自然界中的多酚类物质,因其具有结构多样性,从而表现出多种生物学活性。研究表明:黄酮类化合物对肿瘤细胞的抑制作用是通过多种机制产生的,而细胞周期是其重要的机制之一。文章仅就黄酮类化合物影响细胞周期的靶点、机制等的研究进展作一综述,以期为抗癌药物的研究和疾病治疗提供参考。 Flavonoids are polyphenols that are widely found in nature and exhibit various biological activities due to their structural diversity. Studies have shown that: flavonoids on tumor cells by a variety of mechanisms of inhibition, and cell cycle is one of its important mechanisms. This article reviews the research progress on the target and mechanism of flavonoids affecting the cell cycle, in order to provide a reference for the study of anticancer drugs and disease treatment.