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通过研究孤立性房颤患者外周血中炎症因子的浓度高低,探讨炎症与孤立性房颤之间的关系。方法使用酶联免疫吸附法测定60例孤立性房颤患者的Hcy,IL-6,hsCRP的浓度,同时根据患者入院时房颤持续的时间将患者分为阵发性和持续性房颤两个亚组。结果房颤患者的Hcy,IL-6,hsCRP的水平明显高于对照组,且两组间的差异具有统计学意义(P<0.05);持续性房颤患者的各项指标明显高于阵发性房颤患者(P<0.05);结论孤立性房颤与炎症相关。
By studying the concentration of inflammatory cytokines in the peripheral blood of patients with isolated atrial fibrillation, the relationship between inflammation and isolated atrial fibrillation was explored. Methods The concentrations of Hcy, IL-6 and hsCRP in 60 patients with isolated atrial fibrillation were determined by enzyme-linked immunosorbent assay. At the same time, patients were divided into paroxysmal and persistent atrial fibrillation according to the duration of atrial fibrillation Subgroup. Results The levels of Hcy, IL-6 and hsCRP in patients with atrial fibrillation were significantly higher than those in control group (P <0.05). The indexes of patients with persistent AF were significantly higher than those in patients with atrial fibrillation (P <0.05). Conclusion Isolated atrial fibrillation is associated with inflammation.