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我们用SP法对20例正常乳腺组织、40例乳腺导管上应不典型增生、8例导管原位癌及52例浸润性导管瘤进行ER、PR检测，以探讨乳腺癌发生过程中ER、PR的变化规律，进而为乳腺癌的早期诊断与治疗提供生物学依据。1材料与方法选我院手术送检经病理诊断的乳腺标本120例，其中正常乳腺组
We used the SP method to detect ER and PR in 20 cases of normal breast tissue, 40 cases of atypical hyperplasia of the breast duct, 8 cases of ductal carcinoma in situ, and 52 cases of invasive ductal carcinoma to investigate the ER, PR during breast cancer development. The laws of change provide a biological basis for the early diagnosis and treatment of breast cancer. 1Materials and methods 120 cases of breast specimens pathologically diagnosed by our hospital were selected, including normal breast group