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1例34岁女性患者因带状疱疹自行涂抹3%阿昔洛韦软膏及自行静脉滴注阿昔洛韦0.25 g+0.9%氯化钠注射液100 ml。滴注约2 min后患者出现口唇麻木、胸部不适、头晕、乏力,立即停药,急诊入院,给予吸氧。旋即患者头面部、胸部及四肢近端皮肤出现红斑,口唇发绀、肿胀。停药约8 min患者出现视物不清,血压降至70/40 mm Hg(1 mm Hg=0.133 kPa)。约13 min出现黑曚、恶心、呕吐。经静脉注射地塞米松和肾上腺素、静脉滴注氢化可的松以及泵入多巴胺和去甲肾上腺素等处理,14 h后患者过敏症状完全消失。
A 34-year-old woman with herpes zoster self-applied 3% acyclovir ointment and intravenous infusion of acyclovir 0.25 g + 0.9% sodium chloride injection 100 ml. About 2 minutes after instillation, the patient developed mouth numbness, chest discomfort, dizziness, weakness, immediate withdrawal, emergency admission, and oxygen administration. Immediately patient head and face, chest and limbs near the skin erythema, lips cyanosis, swelling. Approximately 8 min after discontinuation of the patient’s visual acuity, blood pressure dropped to 70/40 mm Hg (1 mm Hg = 0.133 kPa). About 15 minutes black clogs appeared, nausea, vomiting. After intravenous injection of dexamethasone and epinephrine, intravenous infusion of hydrocortisone, and pumped into dopamine and norepinephrine treatment, 14 h after the patient’s allergic symptoms disappeared completely.