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现行标准规定的小儿胃蛋白酶及及蛋白酶合剂的处方为:含糖胃蛋白酶(1∶1200)15～20g,稀盐酸15～20mL,橙皮酊15～20mL,单糖浆100mL,对羟基苯甲酸乙酯(0.5％)10mL,水加至1000mL。因疗效确切、酸甜可口,患者乐于接受,为临床治疗胃蛋白酶缺乏及病后消化机能减退引起的消化不良症的常用制剂。由于现行标准省去胃蛋白酶活力项目检查,且处方中对胃蛋白酶活力影响较大的组分—稀盐酸的含量差异较大,使所配制的胃蛋白酶活力差异悬殊。为充分发挥该制剂的治疗作用,寻求优良制剂,作者求得该制剂的最佳pH值,并探讨了稀盐酸的最佳用量。
The current standard prescription of pepsin and protease mixture of prescription: sugar pepsin (1: 1200) 15 ~ 20g, dilute hydrochloric acid 15 ~ 20mL, orange peel 15 ~ 20mL, single syrup 100mL, ethylparaben Ester (0.5%) 10 mL, water to 1000 mL. Due to the exact effect, sweet and sour, patients are willing to accept, for the clinical treatment of pepsin deficiency and dysfunction caused by digestive disorders commonly used indigestion. As the current standard omission of pepsin activity of the project inspection, and the prescription of pepsin activity greater impact on the components - dilute hydrochloric acid content of the larger differences in the pepsin activity of the preparation differences. In order to give full play to the therapeutic effect of the preparation and seek for excellent preparation, the author obtains the optimum pH of the preparation and discusses the optimal dosage of dilute hydrochloric acid.