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目的探讨影响脑动脉瘤破裂的相关因素,评估和预测动脉瘤破裂风险,降低颅内动脉瘤患者的致残率及病死率。方法经CT及CTA检查确诊脑动脉瘤患者78例,其中分为A组(动脉瘤破裂组)45例,B组(动脉瘤未破裂组)33例,统计分析比较两组患者的性别、年龄、相关病史等情况以及CTA测量的相关指标。结果两组患者性别比较,差异具有统计学意义(χ2=4.562,P=0.033),其中女性更容易破裂;年龄分布,两组差异无统计学意义(t=1.748,P=0.084);高血压病史比较,差异有统计学意义(χ2=8.814,P=0.003);高血脂病史比较,表明两组差异无统计学意义(χ2=1.363,P=0.243)。两组患者在动脉瘤瘤颈宽度、瘤体高度上差异无统计学意义(P>0.05)。动脉瘤瘤体高度和瘤颈宽度比值(AR)两组差异有统计学意义(t=9.978,P=0.003);两组动脉瘤瘤体高度和载瘤动脉长轴的角度值(AN)比较,差异有统计学意义(t=3.182,P=0.002)。结论女性动脉瘤患者,动脉瘤更容易破裂导致蛛网膜下腔出血,高血压很可能是破裂的重要诱因;CTA影像提示瘤体高度和瘤颈宽度比值及动脉瘤生长角度AN很可能是临床预测动脉瘤破裂的重要指标。
Objective To investigate the related factors affecting the rupture of cerebral aneurysm, evaluate and predict the risk of aneurysm rupture and reduce the morbidity and mortality of patients with intracranial aneurysm. Methods 78 patients with cerebral aneurysm diagnosed by CT and CTA were divided into group A (aneurysm rupture group) 45 cases, group B (aneurysm rupture group) 33 cases. The statistical analysis was conducted to compare the gender, age , Related medical history and other related indicators and CTA measurement. Results The gender differences between the two groups were statistically significant (χ2 = 4.562, P = 0.033), of which women were more likely to rupture. There was no significant difference in age distribution between the two groups (t = 1.748, P = 0.084) The difference was statistically significant (χ2 = 8.814, P = 0.003). The comparison of the history of hyperlipidemia showed no significant difference between the two groups (χ2 = 1.363, P = 0.243). There was no significant difference between the two groups in the aneurysm neck width and tumor height (P> 0.05). The aneurysm tumor height and tumor neck width ratio (AR) showed significant difference between the two groups (t = 9.978, P = 0.003). The aneurysm tumor height and angiocentrism , The difference was statistically significant (t = 3.182, P = 0.002). Conclusions Aneurysms are more easily ruptured in women with aneurysm, leading to subarachnoid hemorrhage. Hypertension may be an important cause of rupture. CTA images suggest that the ratio of tumor height to tumor neck width and aneurysm growth angle are likely to be clinical predictors An important indicator of aneurysm rupture.