3D-QSAR analysis of a new type of acetylcholinesterase inhibitors

来源 :中国科学：生命科学英文版 | 被引量 : 0次 | 上传用户：jinnengm9min

【摘要】

：

Acetylcholinesterase (AChE) inhibitors are an important class of medicinal agents used for the treatment of Alzheimer's disease. A screening model of AChE i

【作者】

：

LIU AiLin GUANG HongMei ZHU Li

【机构】

：

InstituteofMateriaMedica,InstituteofChineseMedicalSciences

【出处】

：

中国科学：生命科学英文版

【发表日期】

：

2007年6期

【关键词】

：

ACETYLCHOLINESTERASE (AChE) comparative molecular field ANALYSIS (CoMFA) PHENY

【基金项目】

：

Supported by the Platform Program of National Scientific and Technological Foundation (Nos. 2003DIB1J085 and 2004DKA20240)

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Acetylcholinesterase (AChE) inhibitors are an important class of medicinal agents used for the treatment of Alzheimer's disease. A screening model of AChE inhibitor was used to evaluate the inhibition of a series of phenyl pentenone derivatives. The a

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3D-QSAR analysis of a new type of acetylcholinesterase inhibitors

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