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目的：探讨帕罗西汀佐治慢性前列腺炎（ＣＰ）的临床疗效。方法：治疗组６３例在常规治疗的基础上，口服帕罗西汀，２０ ｍｇ／ｄ至４０ ｍｇ／ｄ，疗程３个月；对照组３８例仅用常规治疗。比较两组治疗前后的前列腺疾患症状评分、生活质量评分、抑郁量评分及焦虑量评分，以及最大尿道闭合压及前列腺内尿液反流程度的变化。结果：治疗组病人上述参数明显下降，其下降幅度均显著大于对照组（Ｐ＜０．０５）。结论：应用帕罗西汀佐治ＣＰ可明显提高临床疗效。
Objective: To investigate the clinical efficacy of paroxetine in treating chronic prostatitis (CP). Methods: In the treatment group, 63 cases were treated with paroxetine, 20 mg / d to 40 mg / d on the basis of conventional treatment for 3 months. The control group, 38 cases, were treated only routinely. Prostate disease symptom score, quality of life score, depression score and anxiety score were compared between the two groups before and after treatment, as well as the changes of maximal urethral closure pressure and urinary reflux degree within the prostate. Results: In the treatment group, the above parameters were significantly decreased, and the decrease was significantly greater than that of the control group (P <0.05). Conclusion: The application of paroxetine and gentamicin CP can significantly improve the clinical efficacy.