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目的对来源于食源性疾病病人腹泻便标本中分离的致泻大肠埃希菌进行耐药情况检测,掌握通化市食源性疾病致病菌的耐药趋势和耐药谱。方法根据CLSI推荐的微量肉汤稀释法定量测定致泻大肠埃希菌的最低抑菌浓度(minimal inhibitory concentration,MIC)。结果来源于通化市食源性疾病患者的41株致泻大肠埃希菌对环丙沙星(CIP)、庆大霉素(GEN)、氯霉素(CHL)、头孢西丁(CFX)、萘啶酸(NAL)、甲氧苄啶/磺胺甲恶唑(TMP/SMZ)、四环素(TET)、头孢噻肟(CTX)等均有不同程度的耐药。结论吉林省通化市食源性疾病患者粪便标本中分离到的致泻大肠埃希菌存在多种抗生素耐药,应高度重视和加强食源性疾病中致泻大肠埃希菌的耐药性监测,以保证食品安全和人类健康。
Objective To detect the drug resistance of diarrhea-causing Escherichia coli isolated from diarrhea and urine samples of food-borne diseases and to grasp the drug resistance and drug resistance spectrum of pathogenic bacteria in food-borne diseases in Tonghua City. Methods The minimal inhibitory concentration (MIC) of Escherichia coli was quantitatively determined according to the CLSI recommended broth microdilution method. Results The results showed that 41 strains of diarrhea-causing Escherichia coli caused by food-borne diseases in Tonghua City were negative for ciprofloxacin (CIP), gentamicin (GEN), chloramphenicol (CHL), cefoxitin (CFX) Nalidixic acid (NAL), trimethoprim / sulfamethoxazole (TMP / SMZ), tetracycline (TET), cefotaxime (CTX) and so on, all have different degrees of resistance. Conclusion There are many antibiotic resistances in diarrhea-causing Escherichia coli isolated from fecal specimens of food-borne diseases in Tonghua City, Jilin Province. Therefore, we should attach great importance to and monitor the drug resistance of Escherichia coli diarrhea in food-borne diseases , To ensure food safety and human health.