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目的 运用文献计量学分析近10年视网膜色素变性(retinitis pigmentosa,RP)的研究现状和发展趋势,比较国 内外RP研究方向的异同。设计 文献计量学分析。研究对象 在网络数据库中检索到的近10年国内外发表与RP相关的论 文。方法 运用计算机在PubMed网络数据库和维普中文科技期刊数据库中逐年检索1994-2003年所有与RP相关的文献,按 不同研究方向归类汇总,采用计数资料的统计学方法进行文献计量学分析。主要指标 逐年RP文献量的定基比和动态数列, RP各研究方向文献量的构成比及RP各相关基因研究的构成比。结果 近10年国内外RP文献量总体呈上升趋势;国外RP 论文数量的增幅和增长速度较平稳,国内RP论文数量增长较快;RP的分子发病机制和治疗是近5年国内外研究的热点。结论 RP越来越多地受到国内外学者的关注,其分子发病机制和治疗仍将是未来研究的热点和难点。
Objective To analyze the research status and development trend of retinitis pigmentosa (RP) in recent 10 years by using bibliometrics and to compare the similarities and differences between RP research directions at home and abroad. Design Document Metrology Analysis. Subjects in the network database retrieved nearly 10 years at home and abroad published RP-related papers. Methods The databases of PubMed and VIP databases were used to retrieve all the articles related to RP from 1994 to 2003 by computer. The bibliographic data were collected and summarized according to different research directions. The bibliometric analysis was performed by using statistical methods of counting data. The main index year after year RP literature fixed base ratio and dynamic series, RP each research direction of the composition of the amount of literature and RP each related gene composition ratio. Results The number of RP papers at home and abroad tended to increase over the past 10 years. The number of RP papers abroad grew steadily and the number of RP papers increased rapidly. The molecular pathogenesis and treatment of RP were the hot topics both at home and abroad in recent five years . Conclusion RP is more and more concerned by scholars at home and abroad, and its molecular pathogenesis and treatment will remain the hot and difficult issues in the future.