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目的探讨襄阳市妇女宫颈人类乳头状瘤病毒(HPV)感染状况,为预防HPV感染和宫颈癌防治提供理论依据。方法采用新型Cervista酶切信号扩大法对襄阳市1 125例妇女进行HPV检测,并对HPV亚型情况进行分析。结果 1 125份宫颈标本中共检出HPV感染360例,阳性率为32.00%。单一组别感染率最高,为62.78%,其中A9组感染率最高,为33.05%;HPV感染的高峰年龄是40~44岁人群;各CIN级别中A9组感染率最高。结论 40~44岁妇女是该市HPV感染的高发人群,而且高危型HPV感染尤其是A9组感染是诱发宫颈癌的主要病因学因素,筛查、控制这部分人群的HPV感染能有效降低该市宫颈癌的发病率。
Objective To investigate the status of human papillomavirus (HPV) infection in women in Xiangyang and provide a theoretical basis for preventing HPV infection and preventing and treating cervical cancer. Methods A new type of Cervista signal amplification method was used to detect HPV in 1 125 women in Xiangyang City and the HPV subtypes were analyzed. Results A total of 360 cases of HPV infection were detected in 125 cervical samples, the positive rate was 32.00%. The infection rate of single group was the highest (62.78%), the infection rate of A9 group was the highest (33.05%); the peak age of HPV infection was 40-44 years old; the infection rate of A9 group was highest in all CIN classes. Conclusions 40-44 years old women are the high incidence of HPV infection in the city, and high-risk HPV infection, especially A9 infection is the main etiological factor inducing cervical cancer. Screening and controlling this part of the population of HPV infection can effectively reduce the city The incidence of cervical cancer.