很早人们就知道,职业性接触多种化学物质可以引起肝脏损害。但目前的情况是仅仅有很少几个工厂所用的化学物质被确认为是肝毒物质。许多实际上属于职业性接触化学物质所致的肝病常被结论为原因不明的肝病。这一矛盾存在的原因是由于接触条件有所不同和用来检测肝功能损害的方法不够灵敏。传统的肝功能试验灵敏性差,而且它不能排除原有的亚临 People have long known that occupational exposure to multiple chemicals can cause liver damage. However, the current situation is that only a few of the chemicals used in the factories have been identified as hepatotoxic substances. Many liver diseases that are actually caused by occupational exposure to chemicals are often referred to as liver diseases of unknown cause. The reason for this paradox is the lack of sensitivity due to the differences in contact conditions and the methods used to detect liver damage. Traditional liver function tests have poor sensitivity and it can not exclude the original subclinical