论文部分内容阅读
目的制备双酚A环氧衍生物的分子印迹聚合物。方法采用沉淀聚合法,以双酚A(bisphenol A,BPA)和双酚A二环氧甘油(bisphenol A diglycidyl ether,BADGE)为双模板分子,α-甲基丙烯酸(methacrylic acid,MAA)为功能单体,三羟甲基丙烷三甲基丙烯酸酯(trimethylolpropane trim ethacrylate,TRIM)为交联剂,偶氮二异丁腈(azodiisobutyronitrile,AIBN)为引发剂,合成了一种高选择性的分子印迹聚合物,运用扫描电镜、红外光谱分析等手段对其形貌、物理特征进行了表征,同时进行了聚合物的静态吸附与动态吸附性能研究。结果合成的分子印迹聚合物(molecularly imprinted polymers,MIPs)对10种化合物的最大平衡吸附量为18.12~27.00mg/g,对10种化合物的吸附略有区别,但差异不大,而非印迹聚合物(non-imprinted polymers,NIPs)则对10种化合物的吸附量为7.10~10.73 mg/g,说明NIPs吸附是由于存在物理吸附。结论 10种目标化合物在MIPs上均有吸附,能够应用于分子印迹-固相萃取-高效液相色谱检测方法的建立。
Aim To prepare molecularly imprinted polymers of bisphenol A epoxy derivatives. Methods The bisphenol A (bisphenol A) and bisphenol A diglycidyl ether (BADGE) were used as double template molecules and methacrylic acid (MAA) A highly selective molecular imprinting was synthesized by using trimethylolpropane trimethacrylate (TRIM) as crosslinking agent and azodiisobutyronitrile (AIBN) as initiator. The morphology and physical properties of the polymer were characterized by scanning electron microscopy and infrared spectroscopy. The static adsorption and dynamic adsorption properties of the polymer were also studied. Results The maximum equilibrium adsorption of 10 compounds for molecularly imprinted polymers (MIPs) was 18.12-27.00 mg / g, which was slightly different for the adsorption of the 10 compounds but not as much as for the non-imprinted polymers Non-imprinted polymers (NIPs) adsorbed 10 compounds of 7.10-10.73 mg / g, indicating that the adsorption of NIPs is due to the existence of physical adsorption. Conclusion All ten target compounds are adsorbed on MIPs and can be applied to the establishment of molecular imprinting-SPE-HPLC method.