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本文用~(31)P核磁共振技术研究在光敏药物Photofrin Ⅱ作用下,DNA分子光敏损伤过程中的构象变化,损伤程度以及该药物与DNA分子可能的结合方式。
In this paper, ~ (31) P nuclear magnetic resonance technique was used to study the conformational changes, the degree of damage and the possible binding modes of DNA and DNA molecules during the photosensitization induced by Photofrin Ⅱ.