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目的探讨慢性阻塞性肺疾病(COPD)患者的呼吸肌力及其与肺通气功能的关系。方法测定43名COPD患者的呼吸肌力(最大呼气压MEP、最大吸气压MIP)与肺通气功能(用力肺活量FVC、第1秒用力呼气量FEV1、第1秒用力呼气量占用力肺活量百分比(FEV1/FVC),探讨呼吸肌力与肺通气功能的相关性。结果 COPD患者呼吸肌力和肺通气功能均明显低于其预计值,最大呼气压(MEP)仅占其预计值的(58.9±9.4)%;最大吸气压(MIP)仅占其预计值的(49.0±9.9)%;FVC%为(60.2±16.0),FEV1%为(36.6±11.2),FEV1/FVC%为(58.8±9.5),经相关分析,呼吸肌力与其肺通气功能呈正相关。结论提示COPD患者肺通气功能及其呼吸肌力均减退,而且二者密切关联,故改善呼吸肌状态有利于提高COPD患者的呼吸功能。
Objective To investigate the relationship between respiratory muscle strength and pulmonary ventilation in patients with chronic obstructive pulmonary disease (COPD). Methods The respiratory muscle strength (maximum expiratory pressure MEP, maximum inspiratory pressure MIP) and pulmonary ventilation (forced vital capacity FVC, forced expiratory volume 1 second FEV1, forced expiratory volume 1 second were measured in 43 patients with COPD. (FEV1 / FVC), and to explore the correlation between respiratory muscle strength and pulmonary ventilation.Results Respiratory muscle strength and pulmonary ventilation were significantly lower than those predicted in COPD patients, and the maximum expiratory pressure (MEP) only accounted for its predicted value (58.9 ± 9.4)%, MIP was only 49.0 ± 9.9%, FVC% was 60.2 ± 16.0, FEV1% was 36.6 ± 11.2, FEV1 / FVC% (58.8 ± 9.5) .Respiratory muscle strength was positively correlated with lung ventilation function.Conclusions suggest that pulmonary ventilation and respiratory muscle strength are decreased in patients with COPD, and the two are closely related, so to improve the state of respiratory muscle is beneficial to improve Respiratory function in COPD patients.