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目的探讨妇女感染HIV(human immunodeficiency virus,HIV)与人乳头瘤状病毒(human papillomavirus,HPV)感染的相关性,为HIV/AIDS(acquired immunodeficiency syndrome,AIDS)妇女宫颈病变的早期发现及治疗提供线索和依据。方法将2011年6月至2012年5月在首都医科大学附属北京地坛医院妇科门诊进行筛查的53例HIV/AIDS妇女作为实验组,58例HIV阴性妇女作为对照组,同时进行TCT(thinprep cytologic test,TCT)及HPV(human papillomavirus,HPV)检测。结果 53例HIV/AIDS妇女TCT异常48例(90.56%,48/53),58例HIV阴性妇女中,TCT异常27例(46.55%,27/58),两组TCT异常概率差异有统计学意义(P<0.05);53例HIV/AIDS妇女中高危型HPV 14例(26.41%,14/53);58例HIV阴性妇女高危型HPV高危型10例(17.24%,10/58),两组感染高危型HPV的概率差异无统计学意义(P<0.05)。结论两组患者的TCT异常有差异,但高危型HPV感染没有差异。
Objective To investigate the correlation between HIV and human papillomavirus (HPV) infection in women and to provide clues for the early detection and treatment of cervical lesions in HIV / AIDS (acquired immunodeficiency syndrome, AIDS) women And based on. Methods From June 2011 to May 2012, 53 HIV / AIDS women screened at Gynecology Clinic of Beijing Ditan Hospital, Capital Medical University were selected as the experimental group and 58 HIV-negative women as the control group. TCT (thinprep cytologic) test, TCT) and HPV (human papillomavirus, HPV). Results Of 53 HIV / AIDS women, TCT was abnormal in 48 cases (90.56%, 48/53). Among 58 HIV-negative women, TCT was abnormal in 27 cases (46.55%, 27/58) (26.41%, 14/53) in 53 cases of HIV / AIDS women, 10 cases (17.24%, 10/58) in high risk type HPV in 58 HIV negative women, There was no significant difference in the probability of HPV infection (P <0.05). Conclusion TCT abnormalities in both groups are different, but there is no difference in high-risk HPV infection.