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目的:观察磷酸铝凝胶联合奥曲肽治疗上消化道大出血的临床止血效果。方法:将82例入选患者随机单盲分为观察组(42例)与对照组(40例),两组患者均给予抗休克、止血等对症处理,对照组在此基础上静脉给药奥曲肽止血,观察组在对照组基础上口服磷酸铝凝胶,观察两组止血时间与止血效果。结果:观察组止血时间(31.8±3.5)h,短于对照组时间(35.5±4.2)h,差别具有统计学意义(P<0.05);观察组48h止血效果与总体有效率(92.9%)优于对照组效果及总体有效率(77.5%),且两组均未见明显不良反应。结论:磷酸铝凝胶联合奥曲肽应急治疗上消化道大出血效果可靠,具备较好的临床推广意义。
Objective: To observe the effect of aluminum phosphate gel combined with octreotide on hemostasis in upper gastrointestinal hemorrhage. Methods: Eighty-two patients were randomly divided into two groups: observation group (42 cases) and control group (40 cases). Both groups were given anti-shock and hemostasis. In the control group, , The observation group oral aluminum phosphate gel on the basis of the control group, to observe the two groups of bleeding time and hemostatic effect. Results: The bleeding time in the observation group was (31.8 ± 3.5) h, shorter than that in the control group (35.5 ± 4.2) h, the difference was statistically significant (P <0.05); the hemostatic effect and overall effective rate (92.9% In the control group and the overall effect (77.5%), and no significant adverse reactions in both groups. Conclusion: The combination of aluminum phosphate gel and octreotide emergency treatment of upper gastrointestinal bleeding is reliable and has good clinical significance.