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目的研究胸膜固定术对恶性胸腔积液患者疗效及其生活质量的影响。方法40例恶性胸腔积液患者采用胞壁佳行胸膜固定术,观察其疗效,术前、术后作血气分析及Karnofsky评分并进行比较。结果有效35例(87.5%),无效5例(12.5%)。血气分析指标pH改善;动脉血氧分压(PaO2)上升;动脉血二氧化碳分压(PaCO2)基本不变;Karnofsky评分术前平均46分,术后平均68分,术前术后比较差异有统计学意义,P<0.01。结论用胞壁佳作胸膜固定术治疗恶性胸腔积液患者,能有效且显著提高其生活质量。
Objective To study the effect of pleurodesis on the efficacy and quality of life in patients with malignant pleural effusion. Methods Forty patients with malignant pleural effusion were treated with good cell wall pleural fixation. The curative effect was observed. Blood gas analysis and Karnofsky score were performed before and after operation. Results were effective in 35 cases (87.5%), ineffective in 5 cases (12.5%). Blood gas analysis indicators pH improved; arterial oxygen pressure (PaO2) increased; arterial partial pressure of carbon dioxide (PaCO2) basically unchanged; Karnofsky score 46 points before surgery, an average of 68 points after surgery were statistically significant differences Significance, P <0.01. Conclusion The best cell wall pleural fixation for malignant pleural effusion patients, can effectively and significantly improve their quality of life.