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作者报导了1例同种异体骨髓移植后由Ⅱ型腺病毒引起的迟发型出血性膀胱炎经PGE_1膀胱内灌注治疗有效的经过。 患者,39岁,女性,因低热双下肢瘀斑,诊断为急非淋白血病M_2型。采用DCMP方案治疗,缓解后为巩固治疗而进行同种异体骨髓移植。供者是患者胞弟,HLA相合,混合淋巴细胞培养阴性。患者有输血后丙型肝炎,肝功能轻度变化,HCV抗体阳性。预处理用马利兰、环磷酰胺。预防GVHD采用环孢素
The authors report the successful treatment of delayed hemorrhagic cystitis caused by adenovirus type-2 by intravesical instillation of PGE 1 after one case of allogeneic bone marrow transplantation. Patient, 39 years old, female, diagnosed as acute non-leukemia M_2 type due to hypovolemic lower extremity ecchymosis. The DCMP regimen was used to treat the allogeneic bone marrow transplant for consolidation therapy. The donor is a patient brother, HLA matched, mixed lymphocyte culture negative. Patients had hepatitis C after blood transfusion, mild changes in liver function, and HCV antibody positive. Pretreatment with Maryland, cyclophosphamide. Prevention of GVHD with cyclosporine