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肿瘤的发生同人类肿瘤的克隆来源密切相关。了解肿瘤的克隆来源对于临床诊断及进一步治疗十分重要。单个体细胞经过有丝分裂形成一个克隆细胞群〔1〕。目前学者们所接受的观点是多数肿瘤细胞都是单克隆细胞组成的,而肿瘤细胞发生的体细胞突变理论也认为单个体细胞在获得一个或
The occurrence of tumors is closely related to the cloning of human tumors. Understanding the clonal origin of tumors is important for clinical diagnosis and further treatment. A single somatic cell mitosis to form a clonal population [1]. At present, scholars accept the view that most tumor cells are composed of monoclonal cells, and somatic mutation theory of tumor cells also believe that a single somatic cell in obtaining one or