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采用反相高效液相色谱法和原子吸收光谱法对不同产地的３１件延胡索药材的两种叔胺生物碱（延胡索甲素和乙素）和８种常见金属元素（Ｆｅ，Ｚｎ，Ｃｕ，Ｍｎ，Ｎｉ，Ｓｒ，Ｐｂ和Ｃｄ）的含量进行了测定。通过统计回归分析发现：药材中延胡索甲素的含量与Ｆｅ，Ｚｎ，Ｍｎ和Ｚｎ／Ｃｕ比具有明显的相关关系（ｒ＝０．７７０２，Ｐ＜０．０１）；延胡索乙素与Ｆｅ含量呈正相关（ｒ＝０．５０５１，Ｐ＜０．０１）；胡延索甲素与乙素的相关性为（ｒ＝０．６５０３，Ｐ＜０．０１）。延胡索经炮制后，Ｆｅ含量明显增加，生物碱含量稍有变化，其它元素含量变化不大。以上结果表明中药延胡索的活性可能是有机成份与金属元素相互作用的结果
Three kinds of tertiary amine alkaloids (fumarateone and B) and 8 common metal elements (Fe, Zn, Cu, Mn) from 31 species of Rhizoma Corydalis from different origins by reversed-phase high-performance liquid chromatography and atomic absorption spectrometry The contents of Ni, Sr, Pb and Cd) were measured. By statistical regression analysis, it was found that the content of corylic acid in medicinal materials was significantly correlated with the ratio of Fe, Zn, Mn and Zn/Cu (r=0.7702, P<0.01); the content of tetrahydropalmatine and Fe was positive. Correlation (r=0.5051, P<0.01); The correlation between Hu Yansuo A and B was (r=0.6503, P<0.01). After processing by Corydalis yanhuensis, the Fe content increased significantly, the content of alkaloids slightly changed, and the content of other elements did not change much. The above results indicate that the activity of Corydalis yanhusuo may be the result of the interaction between organic components and metal elements.