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用广东省医药工业研究所自己首次试产的合成抗癌药羟基脲治疗恶性肿瘤84例,试用结果如下:1.单独应用时,对恶性肿瘤有效率虽不高,但对慢性粒细胞白血病有肯定的疗效;对部分鼻咽癌、恶性黑色素瘤病人也有一定的疗效。2.与放射治疗并用时,可能有增强放射疗效的作用。3.与其它抗癌药综合应用时,病者易于耐受。4.羟基脲毒性反应较轻微,可以口服,使用方便,可在门诊应用。因此认为,该研究所试产的羟基脲是临床上有一定疗效的抗癌药物之一,建议投产供应。
84 cases of malignant tumor were treated with hydroxyurea, a synthetic anticancer drug that was first trial-produced by the Institute of Pharmaceutical Industry of Guangdong Province. The results of the trial are as follows: 1. When used alone, the effective rate for malignant tumors is not high, but for chronic myeloid leukemia Positive effect; on some nasopharyngeal carcinoma, malignant melanoma patients also have some effect. 2. When combined with radiation therapy, may enhance the efficacy of radiation. 3. When combined with other anti-cancer drugs, the patient is easy to tolerate. 4. Hydroxyurea toxicity less serious, can be oral, easy to use, can be used in clinics. Therefore, the Institute of the trial production of hydroxyurea is clinically effective anti-cancer drugs, it is recommended to put into operation.