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目的分析女性更年期原发性高血压患者使用虚燥更平散治疗,探究其机理及疗效。方法选取2014年9月~2015年9月我院收治的女性更年期原发性高血压患者80例,将其随机分为对照组与观察组,各40例,观察两组治疗前后的血压血脂血糖神经递质和雌激素等内分泌相关指标变化。结果 1相较于对照组,观察组血压下降率较高;甘油三酯(TG)、总胆固醇(TC)水平降低,差异均有统计意义(P<0.05)。2与对照组比较,观察组神经免疫相关指标神经肽Y(NPY)较治疗前有所降低,差异有统计意义(P<0.05);神经降压素(NT)、β-内啡肽(β-EP)比较,差异无统计学意义(P>0.05)。3与对照组比较,观察组体内雌二醇(E2)水平较服药前有所降低,差异有统计意义(P<0.05)。结论虚燥更平散有助于降低血压,改善患者体内糖脂代谢、调节体内神经激素及雌激素水平,对女性更年期原发性高血压患者具有较高的疗效,值得临床推广。
Objective To analyze the treatment of climacteric and essential hypertension in women with menopause, to explore its mechanism and efficacy. Methods Eighty female patients with essential climacteric menopause were selected from September 2014 to September 2015 in our hospital. They were randomly divided into the control group and the observation group, 40 cases in each group. The blood pressure, blood glucose and blood glucose Neurotransmitters and estrogen and other endocrine-related indicators change. Results 1 Compared with the control group, the decrease rate of blood pressure in the observation group was higher; the levels of triglyceride (TG) and total cholesterol (TC) were lower, with statistical significance (P <0.05). Compared with the control group, neuropeptide Y (NPY), a marker of neuroimmunology in the observation group, was lower than that before treatment (P <0.05); neurotensin (NT), β-endorphin -EP), the difference was not statistically significant (P> 0.05). Compared with the control group, the level of estradiol (E2) in the observation group was lower than that before the treatment (P <0.05) .3. Conclusions Dryness and flatness can help lower blood pressure, improve the metabolism of glucose and lipids in patients, regulate the level of neurohormones and estrogen in the body, and have a higher therapeutic effect on women with essential hypertension in menopause. It is worthy of clinical promotion.