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目的:探讨肝硬化患者肝功能与凝血功能变化。方法:对74例肝硬化患者,137例健康者进行血清总蛋白(TP),血清白蛋白(ALB),血清总胆红素(TBIL),血清直接胆红素(DBIL),总胆汁酸(TBA),血清丙氨酸氨基转移酶(ALT),血清天门冬氨酸氨基转移酶(AST),和凝血酶原时间(PT)、活化部分凝血活酶时间(APTT)、凝血酶时间(TT)、纤维蛋白原(FIB)进行检测,并对结果进行统计学分析。结果:TBIL,DBIL,TBA,ALT,AST升高,PT,APTT,TT延长,FIB下降。结论:肝硬化肝功能损害与其凝血功能有一定的相关性。
Objective: To investigate the changes of liver function and coagulation function in patients with cirrhosis. Methods: Serum total protein (TP), serum albumin (ALB), serum total bilirubin (TBIL), serum direct bilirubin (DBIL), total bile acid (TBA), serum alanine aminotransferase (ALT), serum aspartate aminotransferase (AST), prothrombin time (PT), activated partial thromboplastin time (APTT), thrombin time ), Fibrinogen (FIB) were detected, and the results were statistically analyzed. Results: The levels of TBIL, DBIL, TBA, ALT, AST increased, PT, APTT, TT prolonged and FIB decreased. Conclusion: Liver cirrhosis with impaired hepatic function has a certain correlation.