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目的 :探讨卵巢癌患者血清中肿瘤坏死因子及白细胞介素 -8测定的临床意义。方法 :用放射免疫法检测38例卵巢癌患者血清中肿瘤坏死因子(TNF)及白细胞介素 -8(IL -8)。结果 :卵巢癌患者血清中TNF及IL-8水平高于正常人(P<0.01)。结论 :测定卵巢癌患者血清中TNF、IL-8对该病的治疗及预后均有一定意义。
Objective: To investigate the clinical significance of serum tumor necrosis factor and interleukin-8 levels in patients with ovarian cancer. Methods: Tumor necrosis factor (TNF) and interleukin-8 (IL-8) were detected by radioimmunoassay in 38 patients with ovarian cancer. Results: The serum levels of TNF and IL-8 in ovarian cancer patients were significantly higher than those in normal controls (P <0.01). Conclusion: The determination of serum TNF and IL-8 in patients with ovarian cancer has a certain significance in the treatment and prognosis of the disease.