目的优化活血舒筋贴膏中挥发油β-环糊精包合工艺条件。方法以挥发油包合率、包合物收率为指标,采用正交试验方法优选搅拌法制备挥发油β-环糊精的最佳包合工艺条件。结果最佳包合工艺条件为:挥发油与β-环糊精比例为1∶8(mL∶g);包合时间为40 min;包合温度为60℃。结论优选出的工艺包合率和包合物收率均较高,工艺合理、可行。 Objective To optimize the inclusion of volatile oil β -cyclodextrin in Huoxue Shujin patch. Methods The inclusion ratio of volatile oil and the inclusion compound yield were taken as indexes to optimize the inclusion process of volatile oil β-cyclodextrin by orthogonal test. Results The optimum conditions of inclusion were as follows: the ratio of volatile oil to β-cyclodextrin was 1: 8 (mL: g); the inclusion time was 40 min; the inclusion temperature was 60 ℃. Conclusion The optimized process inclusion rate and the inclusion compound yield are both high and the process is reasonable and feasible.