患儿,男,2岁8个月,因反复发热伴皮疹,进行性贫血1年余入院。患儿于1984年8月无诱因开始发热,不规则热型,经抗炎对症治愈无效。伴有暗红色的斑丘疹,表面有渗出、出血、结痂、脱屑,皮疹以躯干部为著,并随着体温升高而加重。曾误诊为湿疹,随着病情迁延,患儿面色渐苍白,肝脾肿大,曾以“营养性混合性贫血”“粟粒型肺结核”进行治疗。病情未缓解。患儿在发病过程中常有双耳道流脓现象。体检:T38.2℃,R40次/分,p、132次/分,体重12kg,营养发育差,精神萎糜,面色苍白。躯干部皮肤可见密集的暗红色出血性湿疹样斑丘疹,较粗糙,少数结痂,脱屑、发际周围有散在的类似皮疹。颈部、腋下腹股沟淋巴结肿大,为黄豆,绿豆大小,质地中等,边缘清楚,无触痛。方颅,头发干燥无光泽,颅左顶部可触及约2×2cm~2凹陷。双眼脸浮肿无 Children, male, 2 years and 8 months, due to recurrent fever with rash, anemia more than 1 year admitted to hospital. Children in August 1984 no incentive to start fever, irregular heat type, anti-inflammatory symptomatic cured ineffective. Accompanied by dark red rash, the surface of exudation, bleeding, crusting, scaling, rash to the trunk as a, and with the increase in body temperature and aggravate. Has been misdiagnosed as eczema, with the extension of the disease, children pale complexion, hepatosplenomegaly, had “nutritional mixed anemia,” “miliary tuberculosis” for treatment. The condition did not ease. Children often have ear canal pus phenomenon in the course of the disease. Physical examination: T38.2 ℃, R40 times / min, p, 132 beats / min, weight 12kg, poor nutrition, spiritual wilt, pale. Tight skin dark red hemorrhagic eczema papules visible, relatively rough, a small number of scabs, scaling, the hair around the scattered similar rash. Neck, underarm inguinal lymph nodes, soybean, mung bean size, medium texture, clear edge, no tenderness. Side of the skull, hair dry and dull, cranial left can reach about 2 × 2cm ~ 2 depression. Eyelid face no swelling